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Election Results 11th March 2010

Dacorum BC, Adeyfield West
Con 486 (32.8; -8.6)
Lab 429 (29.0; -13.3)
LD Steve Wilson 362 (24.5; +8.1)
BNP 203 (13.7; +13.7)
Majority 57
Turnout 35.83%
Con hold
Percentage change is since May 2007

Wellingborough BC, Redwell West
Con 570 (57.2; -20.3)
Lab 186 (18.7; -3.9)
BNP 84 (8.4; +8.4)
LD Penny Wilkins 72 (7.2; +7.2)
English Democrats 62 (6.2; +6.2)
Green 23 (2.3; +2.3)
Majority 384
Turnout 37.7%
Con hold
Percentage change is since May 2007

Brandon and Byshottles PC, West
LD John Kelly 477 (55.7)
Lab 380 (44.3)
Majority 97
Turnout not known
LD hold

Lawley and Overdale PC, Central
LD Deborah Crane 381 (62.7)
Lab 227 (37.3)
Majority 154
Turnout 17%
LD gain from Lab

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Its the long genes that stop working

People who read my blog will be aware that I have for some time argued that most (if not all) diseases of aging are caused by cells not being able to produce enough of the right proteins. What happens is that certain genes stop functioning because of a metabolic imbalance. I was, however, mystified as to why it was always particular genes that stopped working. Recently, however, there have been three papers produced: Aging is associated with a systemic length-associated transcriptome imbalance Age- or lifestyle-induced accumulation of genotoxicity is associated with a generalized shutdown of long gene transcription and Gene Size Matters: An Analysis of Gene Length in the Human Genome From these it is obvious to see that the genes that stop working are the longer ones. To me it is therefore obvious that if there is a shortage of nuclear Acetyl-CoA then it would mean that the probability of longer Genes being transcribed would be reduced to a greater extent than shorter ones.