People who read my blog will be aware that I have for some time argued that most (if not all) diseases of aging are caused by cells not being able to produce enough of the right proteins. What happens is that certain genes stop functioning because of a metabolic imbalance. I was, however, mystified as to why it was always particular genes that stopped working. Recently, however, there have been three papers produced: Aging is associated with a systemic length-associated transcriptome imbalance Age- or lifestyle-induced accumulation of genotoxicity is associated with a generalized shutdown of long gene transcription and Gene Size Matters: An Analysis of Gene Length in the Human Genome From these it is obvious to see that the genes that stop working are the longer ones. To me it is therefore obvious that if there is a shortage of nuclear Acetyl-CoA then it would mean that the probability of longer Genes being transcribed would be reduced to a greater extent than shorter ones.
Comments
You can be sure that some of these workers are so incompetent that they would not have the sense needed to put two and two together.
that a baby given crack and covered head to foot in baby talc to cover bruises would not be at risk of any serious injury or death!!
No doubt Gornell will be able to put together another article to explain this away and exonerate the workers.While the general public scratch their heads at such gross negligence.
Compare this to the solicitor who loved his child so much he fled,and his wife simply had an illness called depression.Which millions of us have had and got better.They risk losing a child for mismanagement of their case.